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Sleep Deprivation: Lack of sleep increases dopamine

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  Published: Aug. 22, 2008 found at upi.com 

BETHESDA, Md., Aug. 22 (UPI) -- One night without sleep increases the chemical dopamine in the brain, which may help explain how how the sleep-deprived stay alert, U.S. researchers said.

Using the imaging technique positron emission tomography, 15 healthy participants' brains were tested after being kept awake all night or after being allowed to sleep.

Compared to when well-rested, participants when sleep deprived showed reduced binding of a radiolabeled compound that binds to dopamine receptors in certain parts of the brains.

The researchers concluded that sleep deprivation increases dopamine -- in the striatum part of the brain -- involved in motivation and reward -- and in the thalamus -- involved in alertness. Following sleep deprivation, the rise in dopamine, the researchers say, may promote wakefulness to compensate for sleep loss.

"However, the concurrent decline in cognitive performance, which is associated with the dopamine increases, suggests that the adaptation is not sufficient to overcome the cognitive deterioration induced by sleep deprivation and may even contribute to it," study leader Dr. Nora Volkow, of the National Institute on Drug Abuse, National Institutes of Health in Bethesda, Md., said in a statement.

The study findings are published in The Journal of Neuroscience.

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Sleeping may earn you $10 per hr

 

 Sleeping may earn you $10 per hrWashington, August 2 : It’s no more necessary to get up early in the morning and get ready for work, for NASA is paying people just to sleep.

Well, the U. S. space agency is paying 10 dollars per hour to the subjects participating in its bed rest study, which requires them to spend three consecutive months in bed.

The participants will be paid about 17,000 dollars over the course of the study, which is carried out at the University of Texas.

They spend three months lying down, and the preparation and rehabilitation take up another month.

The study is aimed at finding ways to minimize the debilitating impact of zero gravity in space, which can cause reduction in muscle mass and bone density.

NASA''s Flight Analog Research Unit says one way to recreate such conditions on the ground is for test participants to lie down with head slightly tilted back for 90 days.

Experts behind the project say that the participants in their bed-rest study are providing valuable information for the space program.

"It''s very relaxing at times. This is probably the most I''ve sat still in 10 years," foxnews. com quoted Heather Archuletta, a study participant, as saying. (ANI)

 
 

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